Publikationen

Die Mitarbeiter und Gesellschafter von Isodetect veröffentlichen regelmäßig innovative Forschungsergebnisse aus Industrieaufträgen und F&E-Projekten in weltweit führenden Fachzeitschriften für Umweltwissenschaften und -technologie.

Hunkeler, D., Meckenstock, R.U., Sherwood-Lollar, B., Schmidt, T., Wilson, J.T. (in preparation). A Consensus Guide for Assessing Biodegradation and Source Identification with Compound Specific Isotope Analysis (CSIA). US-EPA.
Thullner, M., Centler, F., Richnow, H.-H., Fischer, A. 2012. Quantification of organic pollutant degradation in contaminated aquifers using compound specific stable isotope analysis – Review of recent developments. Org. Geochem. 42 (12): 1440-1460.
Badea, S.L., Vogt, C., Gehre, M., Fischer, A., Danet, A.-F., Richnow, H.-H. 2011. Development of an enantiomer-specific stable carbon isotope analysis (ESIA) method for assessing the fate of a-hexachlorocyclo-hexane in the environment. Rapid Commun. Mass Spectrom. 25 (10): 1363-1372.
Fletcher, K.E., Nijenhuis, I., Richnow, H.-H., Löffler, F.E. 2011. Stable carbon isotope enrichment factors for cis-1,2-dichloroethene and vinyl chloride reductive dechlorination by Dehalococcoides. Environ. Sci. Technol. 45 (7): 2951-2957.
Hitzfeld, K., Gehre, M., Richnow, H.-H. 2011. A novel online approach to the determination of isotopic ratios for organically bound chlorine, bromine and sulphur. Rapid Commun. Mass Spectrom. 25 (20): 3114-3122.
Knöller, K., Vogt, C., Haupt, M., Feisthauer, S., Richnow, H.-H. 2011. Experimental investigation of nitrogen and oxygen isotope fractionation in nitrate and nitrite during denitrification. Biogeochem. 103 (1-3): 371-384.
Kuntze, K., Vogt, C., Richnow, H.-H., Boll, M. 2011. Combined application of PCR-based functional assays for the detection of aromatic-compound-degrading anaerobes. Appl. Environ. Microb. 77 (14): 5056-5061.
Martinez Lavanchy, P., Dohrmann, A.B., Imfeld, G., Trescher, K., Tebbe, C.C., Richnow, H.-H., Nijenhuis, I. 2011. Detection of monochlorobenzene metabolizing bacteria under anoxic conditions by DNA-stable isotope probing. Biodegradation 22 (5): 973-982.
Miltner, A., Bombach, P., Schmidt-Brücken, B., Kästner, M. 2011. SOM genesis – microbial biomass a significant source. Biogeochem. in press.
Bastida, F., Jechalke, S., Bombach, P., Franchini, A.G., Seifert, J., von Bergen, M., Vogt, C., Richnow, H.H. 2011. Assimilation of benzene carbon through multiple trophic levels traced by different stable isotope probing methodologies. FEMS Microbiol.Ecol. 77 (2): 357-369.
Thornton, S.F., Botrell, S.H., Spence, K.H., Pickup, R., Spence, M.J., Shah, N., Mallinson, H.E.H., Richnow, H.H. 2011. Assessment of MTBE biodegradation in contaminated groundwater using 13C and 14C analysis: Field and laboratory microcosm studies. Appl. Geochem. 26 (5): 828-237
Vogt, C., Kleinsteuber, S., Richnow, H.H. 2011. Anaerobic benzene degradation by bacteria. Microbial Biotechnology 4 (6): 710-724.
Bombach, P., Richnow, H.H., Kästner, M., Fischer, A. 2010. Current approaches for the assessment of in situ biodegradation. Appl. Microbiol. Biotechnol. 86 (3): 839-852.
Bombach, P., Chatzinotas, A., Neu, T.R., Kästner, M., Lueders, T., Vogt, C. 2010. Enrichment and characterization of a sulfate-reducing toluene-degrading microbial consortium by combining in situ microcosms and stable isotope probing techniques. FEMS Microbiol. Ecol. 71 (2): 237-246.
Bombach, P., Hübschmann, T., Fetzer, I., Kleinsteuber, S., Geyer, R., Harms, H., Müller, S. 2010. Resolution of natural microbial community dynamics by community fingerprinting, flow cytometry, and trend interpretation analysis. In: Müller, S., Bley, T. (Hrsg.) High resolution microbial single cell analytics, Advances in Biochemical Engineering, Biotechnology 124 Springer, Berlin: 151-181.
Eisenmann, H., Fischer, A. 2010. Isotopenuntersuchungen in der Altlastenbewertung. In: Franzius, V., Altenbockum, M., Gerhold, T. (Hrsg.). Handbuch Altlastensanierung und Flächenmanagement: 60. Aktualisierung der 3. Auflage. Verlagsgruppe Hüthig Jehle Rehm, München: 47.
Fischer, A., Weber, S., Reineke, A.-K., Hollender, J., Richnow, H.H. 2010. Carbon and hydrogen isotope fractionation during anaerobic quinoline degradation. Chemosphere 81 (3): 400-407.
Herrmann, S., Kleinsteuber, S., Chatzinotas, A., Kuppardt, A., Lueders, T., Richnow, H.H., Vogt, C. 2010. Functional characterization of an anaerobic benzene-degrading enrichment culture by DNA stable isotope probing. Environ. Microbiol. 12 (2): 401-411.
Jehmlich, N., Fetzer, I., Seifert, J., Mattow, J., Vogt, C., Harms, H., Thiede, B., Richnow, H.H., von Bergen, M., Schmidt, F. 2010. Decimal place slope: a fast and precise method for quantifying 13C incorporation levels for detecting the metabolic activity of microbial species. Molecular and Cellular Proteomics 9 (6): 1221-1227.
Liu, F., Cichocka, D., Nijenhuis, I., Richnow, H.H., Fennell, D.E. 2010. Carbon isotope fractionation during dechlorination of 1,2,3,4-tetrachlorodibenzo-p-dioxin by a Dehalococcoides-containing culture. Chemosphere 80 (10): 1113-1119.
Bergmann, F., Abu Laban, N., Meyer A. H., Elsner, M., Meckenstock, R. U. 2010. C and H stable isotope fractionation during strictly anaerobic naphthalene and benzene degradation: Mechanistic implications and potential to assess natural attenuation. Environmental Science & Technology, 2010 submitted.
Penning, H., Sørensen S. R., Meyer A. H., Aamand J., Elsner, M. 2010. C, N and H istotope fractionation of the herbicide isoproturon reflects different microbial transformation pathways. Environmental Science & Technology 44 (7): 2372-2378.
Rosell, M., Finsterbusch, S., Jechalke, S., Hübschmann, T., Vogt, C., Richnow, H.H. 2010. Evaluation of the effects of low oxygen concentration on stable isotope fractionation during Aerobic MTBE biodegradation. Environ. Sci. Technol. 44 (1): 309-315.
Youngster, L.K.G., Rosell, M., Richnow, H.H., Häggblom, M.M. 2010. Assessment of MTBE biodegradation pathways by two-dimensional isotope analysis in mixed bacterial consortia under different redox conditions.
Appl. Microbiol. Biotechnol. 80 (1): 309-31.
Badea, S.L., Vogt, C., Weber, S., Danet, A.-F., Richnow, H.H. .2009. Stable isotope fractionation of g-hexachlorocyclohexane (lindane) during reductive dechlorination by two strains of sulfate-reducing bacteria. Environ. Sci. Technol. 43 (9): 3155-3161.
Fischer, A., Herrmann, S., Richnow, H.H., Vogt, C. 2009. Carbon and hydrogen isotope fractionation during biodegradation of monoaromatic hydrocarbons. Geochim. Cosmochim. Ac. 73 (13): A379-A379.
Fischer, A., Gehre, M., Breitfeld, J., Richnow, H.H., Vogt, C. 2009. Carbon and hydrogen isotope fractionation of benzene during biodegradation under sulfate-reducing conditions: a laboratory to field site approach. Rapid Commun. Mass Spectrom. 23 (16): 2439-2447.
Fletcher, K.E., Löffler, F.E., Richnow, H.H., Nijenhuis, I. 2009. Stable carbon isotope fractionation of 1,2-Dichloropropane during dichloroelimination by Dehalococcoides populations. Environ. Sci. Technol. 43 (18): 6915-6919.
Herrmann, S., Vogt, C., Fischer, A., Kuppardt, A., Richnow, H.H. 2009. Characterization of anaerobic xylene biodegradation by two-dimensional isotope fractionation analysis. Environmental Microbiology Reports 1 (6): 535-544.
Kästner, M., Bombach, P., Richnow, H.H. 2009. Mini-U-Boote im Grundwasser und die mikrobielle in situ-Aktivität. Biospektrum 15 (2): 166-168.
Meyer, A. H., Penning, H., Elsner, M. 2009. C and N isotope fractionation suggests similar mechanisms of microbial atrazine transformation despite involvement of different enzymes (AtzA and TrzN). Environmental Science & Technology 43 (21): 8079-8085.
Stelzer, N., Imfeld, G., Thullner, M., Lehmann, J., Poser, A., Richnow, H.H., Nijenhuis, I. 2009. Integrative approach to delineate natural attenuation of chlorinated benzenes in anoxic aquifers. Environ. Pollut. 157 (6): 1800-1806.
Thullner, M., Richnow, H.H., Fischer, A. 2009. Characterization and quantification of in situ biodegradation of groundwater contaminants using stable isotope fractionation analysis: advantages and limitations. In: Gallo, D., Mancini, R. (Hrsg.). Environmental and regional air pollution. Air, water and soil science and technology series
Nova Science Publ., New York: 41-81.
Cichocka, D., Imfeld, G., Richnow, H.H., Nijenhuis, I. 2008. Variability in microbial carbon isotope fractionation of tetra- and trichloroethene upon reductive dechlorination. Chemosphere 71 (4): 639-648.
Feisthauer, S., Wick, L.Y., Kästner, M., Kaschabek, S., Schlömann, M., Richnow, H.H. 2008. Differences of heterotrophic 13CO2 assimilation by Pseudomonas knackmussii strain B13 and Rhodococcus opacus 1CP and potential impact on biomarker stable isotope probing. Environ. Microbiol. 10 (6): 1641-1651.
Fischer, A., Herklotz, I., Herrmann, S., Thullner, M., Weelink, S.A.B., Stams, A.J.M., Schlömann, M., Richnow, H.H., Vogt, C. 2008. Combined carbon and hydrogen isotope fractionation investigations for elucidating benzene biodegradation pathways. Environ. Sci. Technol. 42 (12): 4356-4363.
Gödeke, S., Geistlinger, H., Fischer, A., Richnow, H.H., Schirmer, M. 2008. Simulation of a reactive tracer experiment using stochastic hydraulic conductivity fields. Environ.Geol. 55 (6): 1255-1261.
Heinzle, E., Yuan, Y., Kumar, S., Wittmann, C., Gehre, M., Richnow, H.H., Wehrung, P., Adam, P., Albrecht, P. 2008. Analysis of 13C labeling enrichment in microbial culture applying metabolic tracer experiments using gas chromatography-combustion-isotope ratio mass spectrometry. Anal. Biochem. 380 (2): 202-210.
Knöller, K., Vogt, C., Feisthauer, S., Weise, S.M., Weiß, H., Richnow, H.H. 2008. Sulfur cycling and biodegradation in contaminated aquifers: insights from stable isotope investigations. Environ. Sci. Technol. 42 (21): 7807-7812.
Meyer, A. H., Penning, H., Lowag, H., Elsner, M. 2008. Precise and accurate compound specific carbon and nitrogen isotope analysis of atrazine: critical role of combustion oven conditions. Environmental Science & Technology 42 (21): 7757-7763.
Thullner, M., Kampara, M., Richnow, H.H., Harms, H., Wick, L.Y. 2008. Impact of bioavailability restrictions on microbially induced stable isotope fractionation. 1. Theoretical calculation. Environ. Sci. Technol. 42 (17): 6544-6551.
Vogt, C., Cyrus, E., Herklotz, I., Schlosser, D., Bahr, A., Herrmann, S., Richnow, H.H., Fischer, A. 2008. Evaluation of toluene degradation pathways by two-dimensional stable isotope fractionation. Environ. Sci. Technol. 42 (21): 7793-7800.
Braeckevelt, M., Rokadia, H., Imfeld, G., Stelzer, N., Paschke, H., Kuschk, P., Kästner, M., Richnow, H.H., Weber, S. 2007. Assessment of in situ biodegradation of monochlorobenzene in contaminated groundwater treated in a constructed wetland. Environ. Pollut. 148 (2): 428-437.
Braeckevelt, M., Rokadia, H., Mirschel, G., Weber, S., Imfeld, G., Stelzer, N., Kuschk, P., Kästner, M., Richnow, H.H. 2007. Biodegradation of chlorobenzene in a constructed wetland treating contaminated groundwater. Water Sci.Technol. 56 (3): 57-62
Cichocka, D., Siegert, M., Imfeld, G., Andert, J., Beck, K., Diekert, G., Richnow, H.H., Nijenhuis, I. 2007. Factors controlling the carbon isotope fractionation of tetra- and trichloroethene during reductive dechlorination by Sulfurospirillum ssp. and Desulfitobacterium sp. strain PCE-S. FEMS Microbiol.Ecol. 62 (1): 98-107.
Fischer, A., Theuerkorn, K., Stelzer, N., Gehre, M., Thullner, M., Richnow, H.H. 2007. Applicability of stable isotope fractionation analysis for the characterization of benzene biodegradation in a BTEX-contaminated aquifer. Environ. Sci. Technol. 41 (10): 3689-3696.
Nijenhuis, I., Nikolausz, M., Köth, A., Felföldi, T., Weiß, H., Drangmeister, J., Großmann, J., Kästner, M., Richnow, H.H. 2007. Assessment of the natural attenuation of chlorinated ethenes in an anaerobic contaminated aquifer in the Bitterfeld/Wolfen area using stable isotope techniques, microcosm studies and molecular biomarkers. Chemosphere 67 (2): 300-311.
Nijenhuis, I., Stelzer, N., Kästner, M., Richnow, H.H. 2007. Sensitive detection of anaerobic monochlorobenzene degradation using stable isotope tracers. Environ. Sci. Technol. 41 (11): 3836-3842.
Rosell, M., Barcelo, D., Rohwerder, T., Breuer, U., Gehre, M., Richnow, H.H. 2007. Variations in 13C/12C and D/H enrichment factors of aerobic bacterial fuel oxygenate degradation. Environ. Sci. Technol. 41 (6): 2036-2043.
Vogt, C., Gödeke, S., Treutler, H.-C., Weiß, H., Schirmer, M., Richnow, H.H. (2007):
Benzene oxidation under sulfate-reducing conditions in columns simulating in situ conditions
Biodegradation 18 (5): 625-636.
Fischer, A., Stelzer, N., Eisenmann, H., Richnow, H.H. 2006. Nachweis des mikrobiellen Schadstoffabbaus in Grundwasserleitern. TerraTech 1-2: 14-17.
Fischer, A., Bauer, J., Meckenstock, R.U., Stichler, W., Griebler, C., Maloszewski, P., Kästner, M., Richnow, H.H. 2006. A multitracer test proving the reliability of rayleigh equation-based approach for assessing biodegradation in a BTEX contaminated aquifer. Environ. Sci. Technol. 40 (13): 4245-4252.
Kästner, M., Fischer, A., Nijenhuis, I., Geyer, R., Stelzer, N., Bombach, P., Tebbe, C.C., Richnow, H.H. 2006. Assessment of microbial in situ activity in contaminated aquifers. Eng.Life Sci. 6 (3): 234-251.
Knöller, K., Vogt, C., Richnow, H.H., Weise, S.M. 2006. Sulfur and oxygen isotope fractionation during benzene, toluene, ethyl benzene, and xylene degradation by sulfate-reducing bacteria. Environ. Sci. Technol. 40 (12): 3879- 3885.
Nikolausz, M., Nijenhuis, I., Ziller, K., Richnow, H.H., Kästner, M. 2006. Stable carbon isotope fractionation during degradation of dichloromethane by methylotrophic bacteria. Environ. Microbiol. 8 (1): 156-164.
Somsamak, P., Richnow, H.H., Häggblom, M.H. 2006. Carbon isotope fractionation during anaerobic degradation of methyl tert-butyl ether under sulfate-reducing and methanogenic conditions. Appl. Environ. Microb. 72 (2): 1157-1163.
Stelzer, N., Fischer, A., Kästner, M., Richnow, H.H. 2006. Analyse des anaeroben Benzolabbaus: Vergleich von In-situ-Mikrokosmen, Elektronenakzeptorbilanzen und Isotopenfraktionierungsprozessen. Grundwasser 11 (4): 247-258.
Stelzer, N., Büning, C., Pfeifer, F., Dohrmann, A.B., Tebbe, C.C., Nijenhuis, I., Kästner, M., Richnow, H.H. 2006. In situ microcosms to evaluate natural attenuation potentials in contaminated aquifers. Org. Geochem. 37 (10): 1394-1410.
Büning C., Pfeifer F., Podwojewski E., Quecke W., Dohrmann A. B., Tebbe C., Kästner M., Richnow H. H. 2005. In situ Mikrokosmenuntersuchungen mit 13C-markiertem Benzol und Toluol zum Nachweis des natürlichen biologischen Abbaus im Grundwasser und zur molekularbiologischen Analyse der abbauaktiven Mikroflora. Altlastenspektrum 14: 137-146.
Fischer, A., Bauer, J., Dietze, M., Gödeke, S., Schirmer, M., Weiß, H., Kästner, M., Meckenstock, R.U., Richnow, H.H. 2005. Konzept zur Quantifizierung des anaeroben in situ-Schadstoffabbaus in BTEX-kontaminierten Grundwasserleitern mittels Deuterium-markierter Substanzen. altlasten spektrum 14 (1): 5-12.
Geyer, R., Peacock, A.D., Miltner, A., Richnow, H.H., White, D.C., Sublette, K.L., Kästner, M. 2005. In situ assessment of biodegradation potential using biotraps amended with 13C-labeled benzene or toluene. Environ. Sci. Technol. 39 (13): 4983-4989.
Kaschl, A., Vogt, C., Uhlig, S., Nijenhuis, I., Weiß, H., Kästner, M., Richnow, H.H. 2005. Isotopic fractionation indicates anaerobic monochlorobenzene biodegradation. Environ. Toxicol. Chem. 24 (6): 1315-1324.
Rückert, M., Großmann, J., Borsdorf, H., Richnow, H.H., Vogt, C., Popp, P., Weiß, H. 2005. Untersuchung natürlicher Abbaupotenziale für altlastbedingte Belastungen in Fließgewässern. altlasten spektrum 14 (3): 125-130.
Somsamak, P., Richnow, H.H., Häggblom, M.M. 2005. Carbon isotopic fractionation during anaerobic biotransformation of methyl tert-butyl ether and tert-amyl methyl ether. Environ. Sci. Technol. 39 (1): 103-109.
Spence, M. J., Bottrell, S. H., Thornton, S. F., Richnow, H. H., Spence, K. H. 2005. Hydrochemical and isotopic effects associated with petroleum fuel biodegradation pathways in a chalk aquifer. J. Contam. Hydrol. 79: 67-88.
Kaschl, A., Vogt, C., Uhlig, S., Nijenhuis, I., Weiss, H., Kastner, M., Richnow, H. H. 2005. Isotopic fractionation indicates anaerobic monochlorobenzene biodegradation. Environ. Toxicol. Chem. 24: 1315-1324.
Vieth, A., Kästner, M., Schirmer, M., Weiss, H., Gödeke, S., Meckenstock, R. U., Richnow, H. H. 2005. Monitoring in situ biodegradation of benzene and toluene by stable carbon isotope fractionation. Environ. Toxicol. Chem. 24: 51-60.
Fischer, A., Vieth, A., Knöller, K., Wachter, T., Dahmke, A., Richnow, H.H. 2004. Charakterisierung des mikrobiellen Schadstoffabbaus mithilfe von isotopenchemischen Methoden. Grundwasser 9 (3): 159-172.
Griebler, C., Adrian, L., Meckenstock, R.U., Richnow, H.H. 2004. Stable carbon isotope fractionation during aerobic and anaerobic transformation of trichlorobenzene. FEMS Microbiol.Ecol. 48 (3): 313-321.
Meckenstock, R.U., Morasch, B., Griebler, C., Richnow, H.H. 2004. Stable isotope fractionation analysis as a tool to monitor biodegradation in contaminated acquifers. J.Contam.Hydrol. 75 (3-4): 215-255.
Vieth, A., Müller, J., Strauch, G., Kästner, M., Gehre, M., Meckenstock, R.U., Richnow, H.H. 2003. In-situ biodegradation of tetrachloroethene and trichloroethene in contaminated aquifers monitored by stable isotope fractionation.Isot. Environ. Health Stud. 39 (2): 113-124.
Fischer, A., Vieth, A., Knöller, K., Wachter, T., Dahmke, A., Richnow, H.-H. 2004. Charakterisierung des mikrobiellen Schadstoffabbaus mit Hilfe von isotopenchemischen Methoden. Grundwasser. 9: 159-172.
Griebler, C., Safinowski, M., Vieth, A., Richnow, H. H., Meckenstock, R. U. 2004. Combined application of stable carbon isotope analysis and specific metabolites determination for assessing in situ degradation of aromatic hydrocarbons in a tar oil-contaminated aquifer. Environ. Sci. Technol. 38: 617-631.
Pfeifer F., Podwojewski E., Quecke W., Richnow H. H. 2003. Charakterisierung des natürlichen biologischen Abbaus von BTEX im Grundwasser des ehemaligen Kokereistandortes Gneisenau 1/2/3/4 mittels Isotopenfraktionierung- Möglichkeiten und Grenzen eines neuen methodischen Ansatzes. Altlastenspektrum 3: 126-135.
Vieth, A., Müller, J., Strauch, G., Kastner, M., Gehre, M., Meckenstock, R. U., Richnow, H. H. 2003. In-situ biodegradation of tetrachloroethene and trichloroethene in contaminated aquifers monitored by stable isotope fractionation. Isot. Environ. Healt. S. 39: 113-124.
Richnow, H. H., Meckenstock, R. U., Reitzel, L. A., Baun, A., Ledin, A., Christensen, T. H. 2003. In situ biodegradation determined by carbon isotope fractionation of aromatic hydrocarbons in an anaerobic landfill leachate plume (Vejen, Denmark). J. Contam. Hydrol. 64: 59-72.
Richnow, H. H., Annweiler, E., Michaelis, W., Meckenstock, R. U. 2003. Microbial in situ degradation of aromatic hydrocarbons in a contaminated aquifer monitored by carbon isotope fractionation. J. Contam. Hydrol. 65: 101-120.
Morasch, B., Richnow, H.H., Schink, B., Meckenstock, R.U. 2001. Stable hydrogen and carbon isotope fractionation during microbial toluene degradation: mechanistic and environmental aspects. Appl. Environ. Microb. 67 (10): 4842-4849.
Vieth, A., Kästner, M., Morasch, B., Meckenstock, R.U., Richnow, H.H. 2001. Charakterisierung des biologischen Abbaus von BTEX im Grundwasserleitern über Isotopenfraktionierung - Feldstudien. TerraTech 10 (5): 37-41.